E.O. is an 8-year-old girl with a history of asthma and allergy to bee stings. She
has been brought to the clinic complaining of a throat infection. Her health care
provider prescribes a course of penicillin to manage her current infection and
cautions her parents to watch her closely for a reaction.
1. What type of reaction is the health care provider concerned about and why?
2. Explain the role of IgE and mast cells in type I hypersensitivity reactions.
Why might E.O. react adversely to the antibiotic with the first use?
3. What would you tell E.O.’s parents to look for when they are assessing for
4. What would you suggest the parents do if a reaction does occur?