Vaginal bleeding

A 33 week client presented to the labor and delivery unit with a rigid abdomen, Vaginal bleeding, and 33-weeknd sharp abdominal pain.  What clinical manifestations would indicate maternal hypovolemic shock

Case Study in Endocrine

Case Study in Endocrine in preparation for Discussion. A 51-year-old unemployed salesman is brought to the emergency department by EMS at 0800, accompanied by his wife.  His wife tells the emergency department nurse that her husband has not been feeling well for the last week, but that when he got up this morning, he was so weak he couldn’t dress and didn’t know where he was.

She also tells the nurse her husband has been taking a cortisone drug for the treatment of his rheumatoid arthritis for the past 2 years, but notes, “We didn’t have the money to buy it this month.”

Assessment data includes:

The patient is dehydrated with dry oral mucous membranes and tongue, poor skin turgor, and sunken eyeballs. His blood pressure is 94/44, and his pulse is rapid and thread.  He is weak, dizzy, and disoriented about time and place.  Diagnostic tests done at 0830 reveal the following abnormal findings:

  • EKG: widening QRS complex and increased PR interval (had peaked T-waves in the ambulance)
  • Sodium: 129 mEg/L (normal range: 135-145 mEq/L)
  • Glucose: 54 mg/ dL (normal range: 70-110 mg/dL)
  • Potassium: 6.2 mEq/L (normal range: 3.5-5 mEq/L)
  • Cortisol: 2 mg/dL (normal for morning draw: 5-23 mg/dL)

The physician determines that the patient is probably suffering from adrenal insufficiency.  The physician orders 5% Dextrose in 0.9 % sodium chloride in water (D5NS) to run at 250 mL/hr intravenously and Hydrocortisone 200 mg IV.  After initiation of the IV fluids and medication, the patient is admitted to an inpatient bed with continuous heart monitoring.

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  1. Briefly explain what adrenal insufficiency is.  Is there one kind or multiple—if so, what are the differences—this should be a discussion of the pathophysiology and presentation of adrenal insufficiency
  2. What are the data that support this diagnosis in this patient? Which of the above does the patient have?
  3. What contributed to the patient developing this condition?
  4. Give a brief explanation of each of the above lab/diagnostic test results, with the pathophysiology behind each.
  5. Identify at least 2 methods that could be used to lower the potassium level if the patient has symptomatic hyperkalemia.
  6. Name 1 priority nursing diagnosis and 1 educational nursing diagnosis.  This condition is potentially deadly for the patient, so the priority diagnosis must reflect a serious response to adrenal insufficiency that the nurse can address
  7. Name a goal statement for each nursing diagnosis.
  8. List 3 nursing interventions for each nursing diagnosis and please be specific about what is essential to teach this patient and his wife

National Center for HIV/AIDS

National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention. Conclusion: how would it recommend to implement the program? Provide evidence for the  recommendations.  Consider the following:

  1. Where should the program be implemented and why?
  2. Should there be a targeted population demographic?
  3. What should the actual implementation process be?

A combination of Fluoxetine and olanzapine

Your patient is a 36-year-old woman with bipolar disorder and anxiety. She has been stable on a combination of fluoxetine and olanzapine for two years.  She is morbidly obese at 340 pounds at 5’5″ in height, has type II diabetes, hypertension, and hyperlipidemia.  She has concerns about her weight and has tried numerous ‘fad diets’ to no avail.  She explains she has lost, at most, 15 pounds and has been able to keep it off for three months.

  • She has three children, one of which is severely disabled, and a husband who has a terminal diagnosis. She expresses worry that her weight will impact her ability to care for her disabled child when her husband dies.  She reports she eats out frequently due to her children’s busy schedules.  She is a stay-at-home mother but gets little exercise and performs no regular physical activity.
  • She reports feelings of shame that she can no longer orgasm on the rare occasions her husband has the energy and desire to be intimate.

Questions:

    • What would be your approach to managing this patient’s weight concern? (Discuss at least two aspects of your approach). Please support your answer with research-based evidence.
    • What would be our approach to the sexual side effects she is experiencing?
    • If you suggested additional medication, look up your state’s prescribing laws. Are PMHNP’s able to prescribe the medication you recommended?

Molarity of Sodium chloride

Molarity of Sodium chloride. attachment1.png

Data Science

Review the Learning Resources for this week related to the topics: Big Data, Data Science, Data Mining, Data Analytics, and Machine Learning.

  • Post a succinct summary on how each topic might apply to nursing practice. Be specific. Note: These topics may overlap as you will find in the readings (e.g., some processes require both Data Mining and Analytics).
    In your post include the following:
    • Explain how you see the data concepts presented aligning with your current practice. What do you need to know to apply these concepts?

With regards to entropy, how does water contribute to the hydrophobic effect?

With regard to entropy, how does water contribute to the hydrophobic effect?

37. Where would you find hydrophobic amino acids on globular protein? Transmembrane protein? Why?
38. What is required for molecular surfaces/interfaces to interact with one another for a sufficient amount of time (such as an antibody/antigen)?
39. Why are weak bonds important to macromolecular structure and enzyme function?
40. Peptide bond synthesis between two amino acids produces a water. If proteins are surrounded by water,
how can this reaction even proceed without violating the 2nd Law of Thermodynamics? Why don’t proteins break down instantly upon synthesis?
41. Why are O-H or O-P (weak bonds) a better source of energy than H2O (strong bonds)?
42. What is the difference between G, G0, and G0′? Which is preferred by biochemists?
43. How can a reaction with a positive G0′ (like malate → oxaloacetate) go forward in the

The development of Cardiac ischemia 

Show the intermediary steps taken from the list from hypertension to the development of cardiac ischemia HTN , Decreased Myocardial DLO2, Increased LV wall Stress, Inc LV systolic pressure, Decreased Cap Density, Increased LV wall thickness, Inc Myocardial V02, Cardiac Ischemia 

Genes and chromosomes in genetics

Genes and chromosomes in genetics. In Barbara McClintock and Harriet Creighton’s experiment with corn, there is eight possible progeny. What

is special about the corn with the colorless waxy (c/wx) phenotype? How else was the experiment confirmed
(Hint: how did they visually confirm the results)?
12. Genes A, B, and C are on a chromosome as shown below. Is this a physical or linkage map? Would you expect the distance between A and C to be more, less, or equal to the sum of the distance between each of
the outside markers and the middle gene (A-B + B-C)? Why?

13. Genes A, B, and C are on a chromosome as shown below. Is this a physical or linkage map? Would you
expect the percentage of recombination between A and C to be more, less, or equal to the sum of the recombination frequencies between each of the outside markers and the middle gene (AxB + BxC)? Why?

14. Why is crossing over between two genes on the same chromosome from 0% to 50%, and not higher?
15. Why is the linkage between two genes on the same chromosome from 50% to 100%, and not lower?
16. How many markers are necessary to map new genes to an exact location on the chromosomes described below using linkage?
a. 50 million base pair human chromosome b. 100 million base pair human chromosome
c. 150 million base pair human chromosome d. 200 million base pair human chromosome
e. 50 million base pair Drosophila chromosome
17. The examples below provide recombination frequency from two-factor crosses. Answer the following: a. For genes ABC, what is the gene order if AB = 30%, AC = 20%, and BC = 38%?
b. For genes XYZ (in order), XY = 25%, and YZ = 35%. Using the equation, what is the recombination frequency for the outside markers, XZ? Why is it not 60%?
c. For genes RST, what are the two possible gene orders if RS = 20%, and ST = 10%? What do you need to know to determine which is correct?
18. Two Drosophila with genotypes AABBCC and aabbcc are crossed to produce a heterozygous offspring,
AaBbCc (the gene order is unknown). This AaBbCc Drosophila is crossed with an aabbcc Drosophila, resulting in the offspring below:
Number: Phenotype:
600 ABC and abc 200 AbC and aBc
150 ABc and abC 50 Abc and aBC
a. Which phenotypes represent the single crossovers?
b. Which phenotypes represent the double crossovers? c. What is the gene order?
d. What does phenotype AbC represent? e. What does phenotype ABc represent?
19. Why were the organisms of classical genetics insufficient for deeper analysis, and what replaced them?

 

An Adrenergic Agonist

Create a Concept Map for each of the following types of drugs: An Adrenergic Agonist, an Adrenergic Blocker, a Cholinergic Agonist, and an Anticholinergic Agent; there should be FOUR concept maps submitted with Four different DRUGs for this assignment.
Each section of the map MUST BE COMPLETED

medications names

1-Adrenergic agonist

2-Adrenergic blocker

3-Cholinergic Agonist

4-Anticholinergic Agent

 

( includes: Mechanism of action, indications, contradictions, side effects, generic in trade name, nursing diagnosis, adverse effects, patient education, patient intervention, and evaluation)