Summarize Thyroid Disorders
Summarize Thyroid Disorders: Hypothyroidism and hyperthyroidism in terms of etiology, pathogenesis, clinical picture, diagnosis, and treatment rationale.
| The 5 General Topics of Disease Summary |
| 1. Etiology & risk factors |
| 2. Pathogenesis: The molecular mechanism of the disease process (How the disease process evolves) |
| 3. Clinical Picture: Signs& Symptoms, Sequelae, and Complications |
| 4. Diagnosis: Labs & tests (as well as screening tests and follow-up tests whenever applicable) |
| 5. Pathophysiologic rationale of treatment |
This summary should cover hypothyroidism and hyperthyroidism, for each, you need to talk about:
- Etiology:
- Most common causes of hypothyroidism in the U.S.
- Most common causes of hyperthyroidism in the U.S.
- Pathogenesis:
Talk about the steps and the molecular mechanisms involved in the development of hypo-& hyperthyroidism and resulting in the clinical picture.
- Clinical Picture:
- Signs& Symptoms: of Hypo- vs hyperthyroidism.
- Complications of hypothyroidism: Myxedema coma
- Complications of hyperthyroidism: Thyroid storm
- Diagnosis:
- Measuring thyroid hormone levels and TSH and how to interpret results to differentiate between primary and secondary hypo- and hyperthyroidism.
- How to follow up the prognosis and response to treatment.
- The pathophysiologic rationale of treatment:
Explain why we use certain medications for treating hypo-& hyperthyroidism in the light of understanding the pathophysiology involved.
This is the textbook for information:
McCance, K.L., Huether, S. E. (2018) Pathophysiology: The Biological Basis for Disease in Adults and Children. (8th Ed) St. Louis, MO. Elsevier Mosby ISBN-13: 978-0323583473 ISBN-10: 9780323583473
