Myxedema coma

What causes myxedema coma?

Hypothyroidism

What causes hypothyroidism?

Thyroid stimulating hormone

Explain how the negative feedback loop controls thyroid levels

Diabetes insipidus

What causes diabetes insipidus (DI)?

Type 2 diabetes mellitus

What is the basic underlying pathophysiology of Type 2 diabetes mellitus?

Hyper-aldosteronism

What is the pathogenesis of primary hyper-aldosteronism?

Cushing’s disease and Cushing’s syndrome

How would you differentiate Cushing’s disease from Cushing’s syndrome?

HHNKS or HHS

Explain the underlying processes that lead to HHNKS or HHS.

Insulin counter-regulatory hormones

The hormones involved in intermediary metabolism, exclusive of insulin, that can participate in the development of diabetic ketoacidosis (DKA) are epinephrine, glucagon, cortisol, growth hormone (insulin counter-regulatory hormones). Describe how they participate in the development of DKA.

Type 1 diabetes

How do genetics and environmental factors contribute to the development of Type 1 diabetes?