Case A Joy and Aiden have met with their GP as part of routine antenatal screening. Initial tests returned the results below. Please comment on their significance. Test Joy Aiden Patient history 23 y.o. female pregnant (6 WG) Caribbean ethnic group 25 y.o. male West African ethnic group RBC 4 x 10^12/L 5.7×10^12/L Hb 112 g/L 170 g/L MCV 93 fL 88 fL MCH 28 pg 30 pg MCHC 302 g/L 340 g/L HbS Solubility Negative Positive The family is referred to a genetic consultant.

Upon meeting with the consultant, Aiden is asked about any genetic diseases running on his side of the family. Aiden shares he does not have genetic conditions but both his parents are carriers for Sickle Cell anemia and have one sister who has the condition. The consultant also is interested in Joy’s family history. She shares that her parent is deceased and did not suffer from any apparent condition. Her brother and sister are healthy. However, her brother is the carrier of sickle cell anemia, and has a daughter suffering from the condition. • What are common signs and symptoms of Sickle Cell Anaemia?

Membrane Fluidity: Designing a membrane You are designing an artificial lipid membrane for use in high temperatures. For each component select the characteristics best suited for high temperatures. Assume that the membrane you design will be used in a temperature that is slightly above its Tm Chain length long Double bonds none Cholesterol (Click to select) V

William notices that a group of ivy plants growing in a cool room of a building grow at a different rate than a group of the same kind of ivy growing in a warm room in the same building. He wants to find out why the two groups of plants grow at different rates. How could he carry out an experiment using all of the steps of a scientific process? Please explain.

Please describe the role of photosynthetic organisms, such as plants, in converting the energy of light to energy that can be used by all living things including the photosynthesizers themselves.

A pet store has two guinea pigs. One has white fur and one has black fur. The white guinea pig has two recessive alleles for fur color (bb). The black guinea pig has one dominant allele (B) and one recessive allele (b) for fur color. What will most likely be the phenotypes of the offspring in a cross between the two guinea pigs? Explain, please.

What are the basic parts of a major theme in molecular biology: the pathway of DNA to RNA to proteins? Please reference a brief summary of what occurs at each stage.

Background. If a pesticide leaks from a storage tank into agricultural soil, one way to prevent it from reaching groundwater is to mix sawdust into the contaminated soil to immobilize the pesticide. A group of scientists is concerned that adding sawdust will negatively impact microbial activity in the soil. The scientists hypothesize that organic compounds in the sawdust will alter the microbial community and that this will slow down the rate that the microorganisms metabolize the pesticide.

Question. Propose two experiments that the scientists should do to test their hypotheses:

1. For the first one, propose an experiment to test whether adding sawdust to soil will impact microbial activity.
2. For the second one, propose an experiment to measure whether adding sawdust to soil negatively impacts microbial biodegradation of the pesticide. Note: assume that the pesticide is a nonpolar organic compound.

In your response, explain how you will set up the experiments. Be sure to include the treatments and controls that you recommend for the scientists and the techniques you propose to use for measurements.