An autoimmune disorder that affects the large intestine

AP is started on a regimen of prednisone because of a crisis in her ulcerative colitis (an autoimmune disorder that affects the large intestine). The information you need to provide AP will need to include when the drug should be taken. In this case, ‘administration of the drug around 8 or 9 am to mimic normal diurnal rhythm if the client has a normal sleep-wake cycle’. But AP works night shifts. What advice will you provide her?