The Role of CRISPR-Cas Systems in Microbial Immunity and Genome Engineering

The Role of CRISPR-Cas Systems in Microbial Immunity and Genome Engineering: Explore the mechanisms by which CRISPR-Cas systems confer adaptive immunity in bacteria and archaea against viral and plasmid DNA. Discuss the potential applications of CRISPR-Cas systems in genome editing, including gene knockout, knock-in, and base editing, and their implications for biomedical research, biotechnology, and agriculture. Consider the ethical and regulatory challenges associated with CRISPR-based genome editing technologies and the importance of responsible use and oversight.

The potential for the treatment of autism

Your 4-year-old nephew has been diagnosed with autism. Your dad doesn’t understand what that means. Explain to your dad the symptoms that comprise autistic disorder, and assess the potential for the treatment of autism. Next, your mom blames your brother, saying he’s too permissive and doesn’t give your nephew enough affection. Include in your essay an explanation to your mom why it is no longer believed that parenting plays a role in autism.

2.  Your 13-year-old sister has been diagnosed with ADHD. Your grandmother has no idea what that means, but she is very worried—she has heard that kids who get diagnosed with this disorder get put in “dumb” classes. Describe to your grandmother the symptoms of ADHD and assess the potential for treatment. In your essay be sure to explain to your grandmother the main concern for children diagnosed with ADHD, and evaluate ways that this concern may be addressed.

Distinct approach to represent climate change

During the first term, we watched two documentary films: Chasing Ice (2012) and Thule Tuvalu (2014). Each of these films takes a distinct approach to represent climate change. Which of these films is the most effective at raising public awareness of climate change and its impacts? By contrast, which film is most likely to motivate climate action? In your answer, make sure to compare and contrast the two films. The answer must develop a coherent essay structure, which includes supporting evidence from at least four references to course material covered in the first and second module

How can you explain the finding that first-generation Americans

How can you explain the finding that first-generation Americans (i.e., the children of immigrants who are born in the United States) may have more psychological problems than those who are recent immigrants?
What difficulties might Hispanic immigrants face when they move to the United States?
In addition to the challenges of stigma, language barriers and lack of insurance, family members may not seek care or may not be fully forthcoming about immigration-related stress or status due to fear of deportation.
How does immigration affect children’s mental health?

Prevalence of Psychiatric Disorders

Once they have arrived, young immigrants must then juggle new stressors, including concerns over their legal status, discrimination, and social marginalization. Thus, youth who are undocumented are at a high risk for experiencing anxiety.

 

Define and structure the core of social and health management

How do you define and structure the core of social and health management? You also have to justify your point of view

Introduction

Social and health management involves various practices and strategies to address the wellbeing of individuals and communities within healthcare and social service settings (Simha and Lemak 2010, p. 221). Developing a comprehensive understanding of this interdisciplinary field’s core components and structure is pivotal in formulating effective interventions and policies that serve the various stakeholders’ diverse needs. This essay will define and structure the core of social and health management by synthesizing insights from multiple perspectives.

Navigating Institutional Dynamics and Evolving Organizational Landscapes in Health Care

The highly institutionalized nature of healthcare systems perpetuates the status quo, as the mechanisms constituting these systems tend to resist externally imposed change (Ferlie et al. 2016, p. 34). Concurrently, the professionalized character of these systems grants professionals a considerable degree of power to maintain stability and control over their work domains. Understanding the power dynamics associated with these institutional and professional structures is instrumental in comprehending the dynamics of stability or change within healthcare organizations. While early literature on institutionalization focused on how organizations respond to normative and regulative forces, leading to isomorphic pressures and homogeneity, subsequent studies unveiled that organizations can accommodate institutional pressures even when dissociated from performance improvement (Ferlie et al. 2016, pp. 27–29). Simultaneously, the sociology of professions literature illuminates how professions exert control over their work, acquire monopolistic positions, and engage in jurisdictional claims over task domains, culminating in occupational closure and power dynamics across professional groups (Ferlie et al. 2016, p. 30). Recent research has integrated the concepts of institutionalization and professionalization by examining competing institutional logics, such as professionalism, managerialism, and market forces, demonstrating how change initiatives must navigate the power dynamics associated with professionalism (Ferlie et al. 2016, p. 33). Recognizing the interplay between institutionalization and professionalization, recent studies have also examined competing institutional logics, such as professionalism, managerialism, and market forces, demonstrating that change initiatives must navigate the power dynamics associated with professionalism (Ferlie et al. 2016, p. 34). This intricate landscape is further complicated by the emergence of new organizational forms and arrangements in response to the healthcare sector’s pressing challenges, including the need to control costs, improve quality, and incorporate new biomedical advances. New organizational structures are also being developed to address the twin challenges of differentiation and integration in healthcare delivery (Ferlie et al. 2016, p. 46). Contrary to the traditional belief that form follows function, the author suggests that in the face of significant environmental changes, alterations in organizational form often precede changes in functions (Chapter 2, p. 40-41). Various factors, including economic pressures, legislative reforms, and the need for greater accountability and integrated service delivery, drive the development of these new organizational forms. However, the governance structure and accountability mechanisms within these new organizational forms are crucial for supporting transformation and addressing the interdependent relationships involved.

Managerial Paradigms and Organizational Cultures in Health Care Transformation

As healthcare systems struggle with the complexities of institutional dynamics and the evolving organizational landscapes, management and organizational culture are critical considerations. Management has assumed an increasingly pivotal role in healthcare systems, transcending the mere translation of policy intent (Ferlie et al. 2016, p. 78). This shift has been accompanied by a transitioning from traditional bureaucratic management to proactive, private sector-style management under New Public Management (NPM) reforms (Ferlie et al. 2016, p. 80). However, the transposition of private sector management models and practices to healthcare settings necessitates contextual nuance and adaptation to account for the unique characteristics of the healthcare sector. Policymakers have imposed culture management and leadership interventions to drive integration and collaboration. However, their effectiveness has been limited due to the top-down imposition and failure to account for entrenched professional cultures (Ferlie et al. 2016, p. 76). Effective knowledge mobilization is paramount in addressing complex “wicked issues” through evidence-based practices like evidence-based medicine (EBM) (Ferlie et al. 2016, p. 77). Concomitantly, workforce development and the introduction of new or changed professional roles can impact existing professional jurisdictions, often encountering resistance from professional associations. To navigate these complexities, hybrid clinical managers who blend managerial and clinical roles can enable professional governance from a distance. Organizational culture, an integral aspect of understanding the nature of healthcare organizations and the forces that shape them, relates to the shared social aspects of organizations, including values, beliefs, and norms that guide behaviour (Ferlie et al. 2016, p. 93). Healthcare organizations are likely to have multiple sub-cultures based on professional groups, specialties, and departments, complicating the assessment and measurement of organizational culture despite the availability of various instruments and approaches. While there is a belief that organizational culture is linked to healthcare performance, this relationship is intricate, contingent, and potentially recursive. Cultural change in healthcare organizations can be classified as first-order (evolutionary) or second-order (radical) change, with models of cultural change often focusing on crises as triggers, leadership, success consolidation, and relearning/re-education (Furrer et al. 2008, p. 2; Ferlie et al. 2016, p. 104). Navigating these intricate managerial paradigms and organizational cultures is essential for driving transformation in health care systems.

Fostering Employee Wellbeing and Collaborative Leadership for Integrated Health and Social Care

Given the issues and the changes ongoing in the health and social care systems, fostering employee wellness and producing good leaders are necessary. Researchers advocate for increased employee wellness within Human Resource Management (HRM) theory and practice, whereby they define wellness as encompassing the psychological, physical, and social components (Guest 2017, p. 26; Bahreini et al. 2021, p. 534). Several factors that contribute to employee wellbeing were subsequently identified. These include job design, balance between job demands and resources, safe working environments, development opportunities, fair compensation, and employment security (Guest 2017, p. 27). HR practices are essential to promote employee wellbeing. Such practices include investing in employees, providing engaging work, creating a positive social and physical environment, allowing employee voice, and providing organizational support (Guest 2017, p. 31). Promoting employee wellbeing through various HR practices and fostering a positive employment relationship could form a core social and health management component. Effective leadership is crucial in interprofessional health and social care teams to support innovation and improvement that can complement the focus on employee wellbeing (Barker 1997, p. 358; Yawson 2016, pp. 262–263; Smith et al. 2018, p. 452). Key themes emerged from the evidence on interprofessional team leadership, including facilitating shared leadership, transformation and change, personal qualities, goal alignment, creativity and innovation, communication, team-building, leadership clarity, direction setting, external liaison, skill mix and diversity, and clinical and contextual expertise (Smith et al. 2018, pp. 458-462). Interprofessional team leadership requires a unique blend of knowledge and skills to support collaboration, shared decision-making, and integrated practices among professionals (Smith et al., 2018, p. 463). Interprofessional team leaders need to find ways to persuade team members from different professions to give up some professional autonomy and integrate their practices. Edmonstone (2020) argues the need to move beyond focusing on leadership development confined to healthcare and instead develop leadership within health and social care systems (p. 351). Systems leadership involves leading across organizational and geographical boundaries, addressing complex issues through inter-organizational networks and non-linear approaches.

Leveraging Strategic Management Theories and Multidisciplinary Research Approaches for Social and Health Management

As social and health management aims to navigate the complexities of institutional dynamics, organizational landscapes, managerial paradigms, organizational cultures, employee wellbeing, and collaborative leadership, it becomes imperative to draw upon strategic management theories and multidisciplinary research approaches (Sagsan 2019, pp. 628–631). Rosenberg Hansen and Ferlie (2016) discuss the applicability of strategic management theories like Porter’s strategic positioning model and the resource-based view (RBV) in public sector organizations, including those in the social and health sectors (p. 1). The usefulness of these strategic management theories depends on three key dimensions: the degree of administrative autonomy, the degree of performance-based budgeting, and the degree of market-like competition (p. 5). For traditional public organizations with low levels of these three dimensions, strategic positioning models like Porter’s may not be as applicable due to the lack of freedom to choose markets, customers, and strategies (p. 8). However, strategic positioning models may be more relevant for more autonomized and market-like service-delivery organizations influenced by New Public Management (NPM) reforms. Regarding the RBV, the focus on value creation and efficient use of resources can be applicable in traditional public organizations, but the emphasis on isolating resources for competitive advantage may not be compatible (p. 11-12). For NPM-influenced organizations with higher levels of the three dimensions, the RBV’s focus on developing dynamic capabilities to adapt to changing environments may be more relevant (p. 12). Examples are provided of English academic health sciences centres and a Danish university hospital where aspects of the RBV could be applied (p. 13-14). A robust evidence-informed approach is crucial to complement the insights from strategic management theories. Evidence discusses the need for an evidence-informed approach in management research, similar to the evidence-based approach used in medical sciences (Tranfield et al. 2003, p. 207; Thorpe and Beasley 2004, p. 335). Systematic reviews can help synthesize research evidence to inform policy and practice in healthcare and other disciplines like education, criminal justice, and social care (p. 209-210). Applying the principles of systematic review from medical sciences to management research can help counteract bias, enhance the knowledge base, and inform policymaking and practice.

Conclusion

The core of social and health management emerges as a multifaceted domain that requires a holistic understanding of institutional dynamics, organizational structures, managerial practices, cultural considerations, employee wellbeing, collaborative leadership, strategic management theories, and multidisciplinary research approaches. Addressing the highly institutionalized and professionalized nature of healthcare systems and understanding the power dynamics associated with these structures is crucial for initiating and sustaining transformative change. As the healthcare sector struggles with pressing challenges, such as cost control and quality improvement, new organizational forms and arrangements become a pivotal consideration. By integrating diverse perspectives and leveraging evidence-informed practices, social and health management can navigate the complexities of this field and drive transformative change within health and social care systems.

References

Bahreini, R., Gholizadeh, M., Gedik, F. G., Yousefi, M. and Janati, A., 2021. Components of contributing conditions to strengthen health system management and leadership capacity building: a systematic review and decision making framework. Leadership in Health Services [online], 34 (4), 527–545. Available from: https://www.proquest.com/docview/2575224107/abstract/7FD1C13379E34FB4PQ/1 [Accessed 7 Mar 2024].
Barker, R. A., 1997. How can we train leaders if we do not know what leadership is? Human Relations [online], 50 (4), 343–362. Available from: https://www.proquest.com/docview/231429531/abstract/572E77564070431EPQ/1 [Accessed 7 Mar 2024].
Edmonstone, J. D., 2020. Beyond healthcare leadership? The imperative for health and social care systems. Leadership in Health Services [online], 33 (4), 351–363. Available from: https://www.proquest.com/docview/2467523539/abstract/6925843F37B24701PQ/1 [Accessed 7 Mar 2024].
Ferlie, E. by E., Montgomery, K. and Pedersen, and A. R., eds. 2016. The Oxford Handbook of Health Care Management. Oxford, New York: Oxford University Press.
Furrer, O., Thomas, H. and Goussevskaia, A., 2008. The structure and evolution of the strategic management field: A content analysis of 26 years of strategic management research. International Journal of Management Reviews [online], 10 (1), 1–23. Available from: https://onlinelibrary.wiley.com/doi/10.1111/j.1468-2370.2007.00217.x [Accessed 7 Mar 2024].
Guest, D. E., 2017. Human resource management and employee wellbeing: towards a new analytic framework. Human Resource Management Journal [online], 27 (1), 22–38. Available from: https://onlinelibrary.wiley.com/doi/10.1111/1748-8583.12139 [Accessed 7 Mar 2024].
Rosenberg-Hansen, J. and Ferlie, E., 2016. Applying Strategic Management Theories in Public Sector Organizations: Developing a typology. Public management review, 18 (1), 1–19.
Sagsan, M., 2019. Knowledge Management Discipline: Test for an Undergraduate Program in Turkey. [online]. Available from: https://www.academia.edu/1474634/Knowledge_Management_Discipline_Test_for_an_Undergraduate_Program_in_Turkey [Accessed 7 Mar 2024].
Simha, A. and Lemak, D. J., 2010. The value of original source readings in management education: The case of Frederick Winslow Taylor. Journal of Management History, 16 (2), 233–252.
Smith, T., Fowler-Davis, S., Nancarrow, S., Ariss, S. M. B. and Enderby, P., 2018. Leadership in interprofessional health and social care teams: a literature review. International journal of health care quality assurance incorporating Leadership in health services, 31 (4), 452–467.
Thorpe, R. and Beasley, T., 2004. The characteristics of performance management research: Implications and challenges. International Journal of Productivity and Performance Management [online], 53 (3/4), 334–344. Available from: https://www.proquest.com/docview/218423369/abstract/CC613D1DC79B4C90PQ/1 [Accessed 7 Mar 2024].
Tranfield, D., Denyer, D. and Smart, P., 2003. Towards a Methodology for Developing Evidence-Informed Management Knowledge by Means of Systematic Review. British Journal of Management [online], 14 (3), 207–222. Available from: https://molloy.idm.oclc.org/login?url=https://search.ebscohost.com/login.aspx?direct=true&db=buh&AN=10833059&site=ehost-live [Accessed 7 Mar 2024].
Yawson, R., 2016. The importance of multimethods and mixed methods research in understanding complexity in leadership. International Journal of Complexity in Leadership and Management, 3, 261.

The IOM Future of Nursing Recommendations

The IOM published report, “Future of Nursing: Leading Change, Advancing Health,” makes recommendations for lifelong learning and achieving higher levels of education.

In 1,000-1,250 words, examine the importance of nursing education and discuss your overall educational goals.
Include the following:

  • Discuss your options in the job market based on your educational level
  • Review the IOM Future of Nursing Recommendations for achieving higher levels of education.
  • Describe what professional certification and advanced degrees (MSN, DNP, etc.) you want to pursue and explain your reasons for wanting to attain the education. Discuss your timeline for accomplishing these goals. Discuss how increasing your level of education would affect how your competitiveness in the current job market and your role in the future of nursing.
  • Discuss the relationship of continuing nursing education to competency, attitudes, knowledge, and the ANA Scope and Standards for Practice and Code of Ethics. Discuss whether continuing nursing education should be mandatory. Provide support for your response.

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The unlicensed assistive personnel reports to the practical nurse

The unlicensed assistive personnel reports to the practical nurse that a resident of the long-term care facility being treated for a Mythic-resistant Staphylococcus aureus (MRSA) infection has purulent wound drainage. When entering the room, the PN observes the UAP using a disinfectant to clean a non-disposable stethoscope. Which action should the PN take? Provide feedback for following proper precautions. Instruct how to clean and decontaminate the area. Discuss aseptic technique guidelines for client care. Teach how to implement protective transmission precautions.

The psychology of learning

The psychology of learning refers broadly to theory and research derived from different types of learning, including classical conditioning, operant conditioning, and observational learning (modeling). Applied behavior analysis draws primarily on operant conditioning as the basis for developing interventions.

•Explain the relationship between evolution and change.

 

•What is the difference between artificial and natural selection?

 

•What must be present in order for evolution to act?

 

The importance of vicariance vs dispersal with regards to bird evolution

The paper seems most plausible to you (1 pt): 5. Section 8.4 has a wonderful discussion with regards to the importance of vicariance vs dispersal with regards to bird evolution. This is an example of how genetic analysis has informed how we understand patterns of evolution over time. In your own words, discuss the history of how our understanding of ratite dispersal has changed over time. This is a ten-point question, so please include an appropriate level of concise detail (10 pts). Note that this assignment is worth 25 points but the 20–this means you five

Interpersonal Process Recording (IPR): Mr. Jones is a 69-year-old retired engineer. He was admitted to the in-patient psychiatric unit the previous day

Interpersonal Process Recording (IPR):  Mr. Jones is a 69-year-old retired engineer. He was admitted to the in-patient psychiatric unit the previous day. His daughter had called the police when he locked himself in his bathroom and refused to come out. She thought he was suicidal. He was brought to the hospital by the police and was admitted on involuntary status. He has been reticent since admission but told his daughter he had no reason to live since his wife died.

Diagnosis: Major Depressive Disorder
Nursing Diagnosis: Risk for suicide.
Mrs. Alvarez is a 34-year-old female who has lived in this country for the past 10 yrs. She is a stay at home mom with three small children. Her husband works two jobs to support the family. Lately, she has been extremely anxious and fears that her children will become ill or injured. This seems to be an unrealistic concern, but she has been unable to sleep well and has lost 15 lbs. in the past month. She is a voluntary admission and states she knows she needs help.

Diagnosis: Generalized Anxiety Disorder
Nursing Diagnosis: Ineffective coping

You will select the role you wish as a client and take turns switching roles. After the conversation, you will document the interactions using the form provided and following the guidelines instructions for each column.

IPR Form Explanation
The IPR is completed with the form to guide you, and the rubric to explain the grading process for content. See attached. Rubric included as well below….

Explanation of the Rubric Criteria for Interpersonal Process Recording (IPR)
Communication (20 verbal entries, ten nonverbal, ten techniques)
Criteria 1 Nursing Interaction (verbal and nonverbal) – Nursing statements and questions demonstrate a positive, caring approach and show insight into the client needs. These interchanges will include the introduction process, but not the more superficial interchanges. Nonverbal communication techniques are also recognized. Thoughts and feelings are identified and documented.
Criteria 2 – The client verbal statements and questions are documented. Nonverbal communication is also observed and interpreted. You may also identify defense mechanism(s) used by the client.
Criteria 3 – All communication techniques used are identified (using titles previously reviewed).
Criteria 4 – All non-therapeutic techniques to be identified and changed to a therapeutic method. If in the review of the interaction, a more appropriate or therapeutic approach (verbal or nonverbal) is identified, document how this response/ statement would be changed