Chest tightness and dyspnea

A 19-year-old female college student presents to the emergency department complaining of chest tightness and dyspnea. She was cutting and trimming the lawn when these

symptoms developed. Rhinorrhea and tearing began soon after she went outside and

preceded the chest discomfort. Going inside did not relieve her symptoms.

During the physical examination, she said, “I have had asthma since childhood, and

my mother and brother also have asthma.” Her respiratory rate was 30 breaths per

minute, and she exhibited the use of accessory muscles of respiration. Breath sounds

were decreased, except for expiratory wheezes. Heart sounds were distant with

tachycardia, but regular.

Identify appropriate laboratory tests. Indicate what therapies might be initiated. What worsening signs and symptoms may manifest?

 

 

 

 

 

CASE STUDY II

Mr. S. is a retired 69-year-old county attorney who was on a buying trip with his wife

looking for old, classic cars in the high, mountainous country of Colorado when he

became extremely short of breath, much more than usual. His alarmed wife took him

to a multispecialty medical clinic for evaluation.

Upon admission, Mr. S. was restless and dyspneic. His history revealed a habit

of smoking two packs of cigarettes a day for 45 years (90 pack years). During the past

few years, Mr. S. noticed a cough each morning on arising. Recently, while working in

his flower garden, he had to stop at times to catch his breath. He stated, “Even while

I’m watching television, it is sometimes hard to breathe.”

On examination, the anteroposterior diameter of his chest was enlarged, and upon

percussion, his chest exhibited a hyperresonant sound. A chest radiograph was

taken, and pulmonary function tests were done. The chest radiograph revealed a

flat, low diaphragm with lung hyperinflation, but clear fields. Pulmonary function tests

showed decreased tidal volume and vital capacity, increased total lung capacity, and

prolonged forced expiratory volume.

 

Which pulmonary disease is exhibited by Mr. S.’s symptoms? Justify your answer.

Evaluating the Use of statistics in a study?

What is the most important thing a reader should do when evaluating the use of statistics in a study? Group of answer choices

Check to see if the authors made any math errors.

Evaluate whether the tables and graphs were informative.

Determine whether the sample size was adequate.

Identify whether or not the assumptions for the statistical method were met

A logical Discussion on sampling

Discussion #5:  Review the following concepts so you can provide a logical discussion on sampling: parameters or attributes of the population representativeness of the defined population appropriateness of the sampling plan to the research design appropriateness and justification of the sample size evidence that the rights of human participants (subjects) have been protected  Now develop your own sampling strategy based upon your PICOT question by responding to the questions below.

Make sure you support your answers with the literature. Provide both in-text citations and a reference list. A State your PICOT. Define your target population and proposed sample.

B Discuss your sampling approach in terms of its nature, use, advantages, and disadvantages.

C Indicate the inclusion and exclusion criteria. Exclusion criteria must be other than “Participants are excluded if they do not meet inclusion criteria.”

What else could exclude participants from your research study? D Identify the sample size and discuss how the number of participants was determined. E Discuss potential threats to internal and external validity as a source of sampling bias.

F What is your Cosmic Question  (This is a question you ask your peers to respond to based on the chapter discussed in class this week: Sampling Strategy).

Remember, the aim of the cosmic question you propose should enable others to critique your sampling strategy.

Complaining of Bloody diarrhea

Mrs. Agarwal is 35 years old and is complaining of bloody diarrhea. She claims that she was in good health “except for the last three months when this condition started.” In the past three months, Mrs. Agarwal has had four instances of bloody diarrhea, where it would last for a few days and resolve.

Her husband claims that her appetite is “just not what it used to be” while he tells you she has been “feeling more tired than usual.” She says she has a very stressful job and has been experiencing frequent tension headaches, for which she takes one 200 mg Advil daily.

Her husband adds that she “smokes one pack of cigarettes a day” to relieve her stress. Mrs. Agarwal reports abdominal tenderness upon palpation. The physician suspects that Mrs.

Agarwal has inflammatory bowel disease. From your pharmacology class, you know that some of the treatments Mrs. Agarwal may receive include anti-diarrheal medications, immunosuppressive agents, and corticosteroids.

Questions

-With a diagnosis of inflammatory bowel disease, what could be discussed with Mrs. Agarwal regarding changes to her diet and lifestyle? How would you present this information to her and her husband?

-Mrs. Agarwal receives an oral prescription for the corticosteroid, prednisone (Winipred), for seven days. How would you educate Mrs. Agarwal regarding the mechanism of action of this medication? What side effects could she expect?

-Mrs. Agarwal is worried about the potentially dangerous side effects of taking an immunosuppressive agent, such as azathioprine (Imuran). She states, “…I read on the Internet that you can get cancer or something even worse, from taking immunosuppressive agents…”

What is your initial response to Mrs. Agarwal’s concern regarding the potential serious side effects?

-Mrs. Agarwal returns after 4-weeks with a severe flare-up for which she has been prescribed a corticosteroid suppository.

Mrs. Agarwal wonders why she got a different medication that is administered rectally. What should you tell her about why this route of administration was chosen? How would you instruct her on how to administer it?

-Mrs. Agarwal is experiencing severe diarrhea with this current flare-up, having to go to the toilet 12-14 times per day. She has been taking the anti-diarrheal, loperamide (Imodium), for 48 hours to help relieve her diarrhea.

Mrs. Agarwal has complaints of dry mouth, lethargy, tachycardia and voiding once every 24 hours and states she is concerned about these side effects.

List 3 questions and the rationale for asking the questions, being very specific, that you would like to ask Mrs. Agarwal based on the information in this question.

Shortness of air, volume overload and Gangrene

This is a 70 y/o Caucasian male who has had 4 admissions in the last 4 months for shortness of air, volume overload and gangrene of his right foot which he had a transmetatarsal amputation of. His current admission is for increased oxygen needs (up to 4-6L NC from 2L), SOA with talking and any activity and BLE edema.

He reported increased SOA when lying flat and that it has been worsening for the last two days as has his edema. Upon presentation he is noted to also have renal insufficiency (Crt now 3.7), anemia (Hgb 7.3), volume overload (BNP 20,692).

He presented with a wound vac on his right foot from his recent transmetatarsal amputation which was removed yesterday by vascular and rebandaged.

He reports chronic aching pain in his back and neuropathy in his feet, otherwise no new onsets of pain, numbness or tingling.

Met with patient and his children this afternoon at bedside regarding patient’s current status, prognosis and goals of care. He is seen resting in bed with his daughter and son at bedside.

He is wearing his nasal cannula initially but is obviously easily short of air and tiresome. He states this make him very anxious and he feels more comfortable wearing the Bipap which he asks to be place on him within a few minutes of me bring in the room. He states he is having chest heaviness, denies pain, and shortness of breath.

He is tearful at times during our conversation and states he feels broke and is tired of living this way.

Pt is frustrated about being stuck in bed and wats very badly to be able to return to his home.

We discussed the need to be stronger and that in his current state it is not safe for him or his children (who will be assisting with cares if this were to happen). He understands this but is tearful and clearly disappointed.

We discussed the possibility of needing an above the knee amputation as his RLE has severe vascular disease and his wounds are not healing on his foot, opening him up to additional infections.

He states “what’s the point” and that he is absolutely not interested in further amputation.

We went on to discuss the possible need for a pacemaker as he has become bradycardic, is not tolerating beta blockers, and has had pauses. We discussed the process of the procedure, healing time, risks and benefits and he feels that he would be okay with this if and when the cardiologist says it is necessary.

Palliative care and hospice are also discussed in detail and he understands these options as well.

He is not ready to make a decision regarding aggressive care with palliative support vs hospice and would like time to discuss these options with his family.

All questions were answered and the patient was encouraged to discuss the information with his children as well as continue to ask questions and accept support as needed.

Contact information was shared and we will follow up with him tomorrow for further questions and thoughts.

Contacted by attending physician later this evening.

She has had an additional conversation with the patient and family and they have decided to take the patient home on hospice care.

Current Medications:

Atorvastatin 40mg PO HS

Bumex 1mg PO BID

Hydralazine 50mg PO TID

Isosorbide Mononitrate 60mg PO Daily

Sodium Bicarbonate 650mg 1 tab PO Daily

Flomax 0.4mg PO HS

Lispro Insulin 5 units SQ ACHS

Glargine Insulin 5 units SQ qAM

Apixaban 2.5mg PO BID

Ferrous Sulfate 325mg PO BID

Trazadone 100mg PO HS

Furosemide 40mg IV BID

Ocean Spray 1 spray nasally Q2H PRN nasal dryness

Duoneb 0.5-3mg/3ml 3ml IH q2h PRN Shortness of breath

Norco 5/325mg 1 tablet PO Q4H PRN Pain 7-10/10

Acetaminophen 650mg PO q4h PRN Pain 2-6/10

Ondansetron 4mg IV q6h PRN N/V

Polyethylene Glycol 17GM PO Daily PRN Constipation

Glucose Tabs 3 tabs PO PRN BG <50

 

Allergies: NKA

PMHx: DM2, HTN, HLD, CAD, Diastolic HF (EF 40-45% with moderate hypokinesis 6/2020), Ischemic Cardiomyopathy CKD3, MI (2009), Peripheral Neuropathy, Gangrene, Osteomyelitis, Cellulitis, COPD, Chronic Wound, Atrial Fibrillation, Hyponatremia, BPH, Chronic Foley for Urinary Retention, Anxiety, Depression, Alcohol Abuse (last drink 3/2021), former smoker

Tetanus Vaccine 4/2021, Patient states he has had his pneumonia vaccine (unknown date) and had a flu shot last year (2020). He has not received his Covid vaccine.

 

Soc and Substance Hx:

Patient is retired and widowed. He is a former smoker that quit in 2002 and a former alcoholic who quit in March of 2021. He denies illicit drug use.

Prior to his serial admissions, he lived at home alone and was able to complete all ADLs without assistance, did all his own shopping and had a group of friends he hung out with regularly.

He enjoys working in his yard and likes to brag it’s the best on the street.

His daughter, his son and his son’s family live nearby and he sees them often. Family is his passion. Prior to March of this year, he has a history of being very compliant with medications, doctor appointments and preventative care.

In March he drank heavily after being sober for 6 months and decided he was done with alcohol and medication.

Fam Hx:

Mother died from heart disease

Father died from throat and tongue cancer

1 Brother: alive with prostate cancer and heart disease

1 Sister: alive and healthy

2 children: alive and healthy

Surgical Hx:

Cardiac Stents 2009, CABG 2017, Right transmetatarsal amputation 2021, Aortagram with runoff and right femoral-tibial bypass 2021

Mental Hx: Anxiety and Depression, Denies suicidal or homicidal ideation.

Violence Hx: Pt with chronic debility, unsafe to be at home alone. Family unable provide 24/7 care.

Reproductive Hx: unknown if sexually active

ROS:

GENERAL: Weight gain of almost 50lbs since April, increasing weakness

HEENT: Eyes: No vision or hearing changes, denies congestion, sore throat, dry mouth

SKIN: Denies dry skin, itching

CARDIOVASCULAR: Constant chest pressure which he feels is related to his breathing. Reports swelling in his BLE. Denies palpitations and chest pain.

RESPIRATORY: Shortness of breath, dyspnea on exertion, Bipap dependent, denies cough.

GASTROINTESTINAL: Denies anorexia, nausea, vomiting, diarrhea, or abdominal pain.

GENITOURINARY: Chronic foley

NEUROLOGICAL: Persistent headache 5/10, Dizziness at times. BLE neuropathy. Denies syncope.

MUSCULOSKELETAL: Constant low back pain 5/10, describes as an ache and repositioning improves the pain while lying in one position too long aggravates it.

HEMATOLOGIC: Denies bleeding or abnormal bruising.

LYMPHATICS: No enlarged nodes.

PSYCHIATRIC: Reports depression in regards to his current state and health and anxiety in regards to his breathing and end of life.

ENDOCRINOLOGIC: Denies cold or heat intolerances, excessive thirst or dry mouth.

ALLERGIES: No history of asthma, hives, eczema, or rhinitis.

O.

VITAL SIGNS: 157/87, 98% on 35%FiO2, 65bpm, 23 RR, 35.6̊ C, 243lbs, BMI 32.1

GENERAL APPERANCE: alert, awake, oriented, pleasant, chronically ill appearing, respiratory support

HEENT: atraumatic, normocephalic, PERRLA, dry mucosal membranes

NECK: non-tender, no JVD

CARDIOVASCULAR: irregular rate and rhythm, normal capillary refill in upper extremities, delayed capillary refill in left lower extremity.

RESPIRATORY: DOE, shallow rapid breaths, decreased breath sounds and wheezes throughout, symmetric expansion, increased work of breathing noted with accessory muscle use.

ABDOMEN: non tender, soft, rounded, normal bowel sounds

GENITOURINARY: chronic foley with clear yellow urine

EXTREMITIES: 2+ BLE and BUE edema, Right toe amputation- covered with dressing, not inspected

MUSCULOSKELETAL: normal inspection, MAE

NEUROLOGICAL/CNS: A&Ox4, normal speech, CNII-XII intact

SKIN: Bandage to right foot- CDI

PSYCHIATRY: Depressed and anxious, not homicidal or suicidal, no hallucinations.

Diagnostic results:

Crt 3.7, GFR 17, BUN 76, BNP 20692, Albumin 2.2, RBC 2.54, Hgb 7.3, Hct 23.3

CXR: Pulmonary edema

A.

Differential Diagnoses:

  1. Acute on Chronic Respiratory Failure

When airways are unable to get a sufficient amount of air to the lungs resulting in less oxygen and more carbon dioxide build up due to narrowing or damage due to an ongoing condition, this is chronic respiratory failure (Marcin, 2018a). In this patient’s situation, his respiratory failure is due to his COPD and smoking history.

His acute exacerbation in related to volume overload for this admission. Supportive findings include his increased need for pressure support oxygen, increase from baseline oxygen needs, CXR results and abnormal lung sounds.

  1. Chronic Kidney Disease (CKD) IV

Moderately to severely damaged kidneys with a glomerular filtration rate (GFR) between 15 and 30 is labeled as Stage 4. RM’s GFR is 17 and he is consistent with the symptoms of swelling and back pain as well as additional complications that often accompany CKD: anemia and hypertension (American Kidney, 2021).

  1. Diastolic Heart Failure

The heart is responsible for pumping the blood through the body to provide oxygen rich blood to tissues and return blood to the lungs to reoxygenate it and send it back out to the body.

When the left ventricle is unable to relax as it should, the amount of blood sent out to the body is less than it should be and there is congestion as the blood that was not sent out backs up waiting to exit the heart (American Heart, 2017). Heart failure diagnosis is supported by extremity edema, pulmonary edema and BNP of >20K.

  1. Anemia

Anemia is the most common blood disorder and happens when there is a decline in the amount of red blood cells in the body. RBCs carry hemoglobin which is necessary to transport oxygen to around the body.

This patient is at an exceptionally high risk due to his CKD and HF as well as advanced age (American Society, 2021). Supporting documentation for this patient include Hgb 7.3, Hct 23.3 and RBC 2.54.

  1. Non-Healing Right Foot Wound r/t PVD

Peripheral Vascular Disease (PVD) is caused by blood vessels of the body, with the exception of the heart and brain, narrowing or becoming blocked due to arteriosclerosis, spasms and clots.

It often leads to organ damage and digit amputation at the least. Risk factors of PVD associated with this patient include age over 50, overweight, HLD, HTN, HF, CAD, DM, smoking and kidney disease (Marcin, 2018b).

This patient has a non healing wound which is very typical for patients with PVD as the blood flow is not strong enough to perfuse the area with oxygenated blood to promote healing.

P.

Case Management and RN notified of patient’s decision, please provide choice letter for hospice company to patient/ family.

May discontinue all medications except Norco

Ativan 1mg PO TID

Ativan 0.5mg PO q2h prn anxiety

May D/C Home with Hospice once arrangements are made

Please call for concerns or needs, will follow along until patient can transfer.

REFLECTION: This is a complex case that I have had the opportunity to participate in on both the internal medicine side in my previous clinical rotation as well as on the palliative care side in this clinical rotation. This patient has glowed since day one when his family visited.

He told stories of gardening and working in his yard regularly. Amputation was difficult for him to digest but knowing he could still potentially get around made it worth it to him.

Unfortunately, his organs had other thoughts and were too tired to get him back to an acceptable quality of life.

He slowly shared his frustration and depression regarding his situation throughout the course of his four hospitalizations.

Medically he understands that he is not curable with COPD, CKDIV and HF diagnoses. He understands his diseases are manageable with assistance but that he will continue to slowly decline regardless of interventions provided making aggressive care futile.

Being quite active and independent was a huge change for this patient and put him at a higher risk of depression. He had support in his children, however, they both work full time jobs and could not be at his side as consistently as he would have liked.

I agree with offering this patient the options of aggressive care with palliative support versus hospice care.

Looking at this case as a whole from the internal medicine stance as well as the palliative stance, I would educate this patient earlier on regarding the fight he had in front of him and the importance of early mobilization and discuss his acceptable quality of life and care goals.

I also would have started him on an antidepressant and offered more mental and emotional support options.

This case taught me to evaluate the mental and emotional health of my patients early on in the disease process and to closely follow them for changes and needs.

Giving patients the attention and support they need either independently or through resources, is essential to their long-term success fighting a major health challenge.

What additional treatment options and/or orders would you recommend for this patient?

Domains of Perioperative nursing

Discussion on the four specific domains of perioperative nursing provided to the surgical patients: (patient safety, physiologic response, behavioural responses, and the health system), to exemplify the continuum of care in achieving desired patient outcomes

The International Council of Nurses

From the International Council of Nurses (ICN) Code of Ethics for Nurses, Element1 is ‘Nurses and People’.

In addition to the information given in the scenario, you are also aware that recovery staffs in the healthcare facility regularly administer narcotic analgesia as part of their pain management protocol.

Provide two (2) examples of how EN Baxter can apply Element 1 in this scenario. In your response, include reference to Mr Smythe’s cultural beliefs about analgesia.

Routine care

A female is 28 years old and the male is 29 years old. They report they have not had any routine care since college. They are concerned that they can not get pregnant.

CC: “We do not know where to begin so we thought we would have complete physicals. We know we need immunizations. Someone told us we should also get checked for chlamydia infections.”

Past medical history: None

Vital signs: Female: Blood pressure: 126/88; height, 5΄΄; weight, 185 lbs.

Male: Blood pressure: 130/98; height 6 feet, weight 170 lbs

Questions:

  1. Subjective data: What subjective data should the APN obtain? How is the complaint investigated ie HPI?
  2. This area should discuss history, ROS, and HPI format.
  3. 2. You will reassess to verify the presented information. For what additional objective data will you assess and why?
  4. 3. What co-morbid conditions should be investigated through the physical exam, how and why?
  5. 4. What National Guidelines are appropriate to this case? What do the guidelines state?
  6. What level of evidence supports these guidelines?
  7. 5. What diagnostic tests will you order? Why do they apply to this case? What is the sensitivity and specificity? When it is positive or negative what does that mean?
  8. 6. What is your medical diagnosis? What are the differential diagnoses?
  9. 7. Treatment plan should clearly state what exact orders you are ordering. All medications must have a name, a dose, a route, and a frequency. The diet must be specific. The diagnostics must be specific. Do not say XRAY say type of Xray ie AP/Lat chest Xray
  10. 8. Are there any Healthy People 2030 goals that you should consider? How will you promote health with this case? How does it meet the 2030
  11. 9. What specific patient teaching is needed? Do not say “how to use an inhaler” state exactly what you will teach
  12. 10. What billing codes would you recommend? This must include the CPT code for outpatient office visits. ICD classify diagnoses ie HTN i10, CPT codes are 992–, Describe the difference between the first visit billing code and follow up billing code.11. Follow up and evaluation. When will the next office visit occur? What will you assess? How will you revise the plan based upon this assessment? For instance, if you are assessing the HgbA1c and it is 9, what will you order? If it is 6.5 what will you do?

Alternate way of Doing research

Can you propose an alternate way of doing research on willing human subjects which would protect the dignity of the individual and at the same time yield the necessary information we need to advance medical science?

Increased Hydrostatic pressure in the hepatic portal vein

Cirrhosis leads to scarring and increased hydrostatic pressure in the hepatic portal vein. Explain why this increased venous pressure causes net filtration to increase in the hepatic capillaries, leading to ascites (swollen and fluid-filled interstitial space of the abdomen).