An understanding of the cardiovascular and respiratory systems is a critically important component of disease diagnosis and treatment. This importance is magnified by the fact that these two systems work so closely together. A variety of factors and circumstances that impact the emergence and severity of issues in one system can have a role in the performance of the other.

Effective disease analysis often requires an understanding that goes beyond these systems and their capacity to work together. The impact of patient characteristics, as well as racial and ethnic variables, can also have an important impact.

An understanding of the symptoms of alterations in cardiovascular and respiratory systems is a critical step in diagnosis and treatment of many diseases. For APRNs this understanding can also help educate patients and guide them through their treatment plans.

In this Assignment, you examine a case study and analyze the symptoms presented. You identify the elements that may be factors in the diagnosis, and you explain the implications to patient health.

Assignment (1- to 2-page case study analysis)

Scenario 1: 76-year-old female patient complains of weight gain, shortness of breath, peripheral edema, and abdominal swelling. She has a history of congestive heart failure and admits to not taking her diuretic, as it makes her “have to get up every couple hours to go to the bathroom.” She now has to sleep on two pillows in order to get enough air.

In your Case Study Analysis related to the scenario provided, explain the following

. The cardiovascular and cardiopulmonary pathophysiologic processes that result in the patient presenting these symptoms.
. Any racial/ethnic variables that may impact physiological functioning.
. How these processes interact to affect the patient.

Develop a presentation about covid-19 explaining the levels of evidence in selected peer-reviewed articles and the strengths of using systematic reviews for clinical research.
Your response to this Assessment should:
Reflect on the criteria provided in the Rubric. Develop a PICOT question to address your clinical issue of interest-Covid-19.
Using the keywords from the PICOT question, search at least four different databases in the Walden Library to identify at least four relevant peer-reviewed articles at the systematic-reviews level.
Identify and briefly describe your chosen clinical issue of interest.(Covid-19)
Describe how you developed your PICOT question focused on your chosen clinical issue of interest.
Identify the four research databases that you used to conduct your search for the peer-reviewed articles that you selected.
Provide APA citations for the four peer-reviewed articles that you selected.
Describe the levels of evidence in each of the four peer-reviewed articles you selected. Be specific and provide examples.
Explain the strengths of using systematic reviews for clinical research. Will be translated into a 7-slide presentation.

The goal of this exercise is to use alternative models of gene action. Consider a hypothetical locus that influences the weight of a chicken. The locus has alleles H (heavy) and L (light). When fed the same diet, HH chicken weigh 3.5 kg, and LL chicken weighs 2 kg. Answer the following questions and show your work supporting your answers:

1a) [10 points] For the HL chicken indicate the expected weight if the locus exhibits no dominance.

1b) [25 points] For the HL chicken indicate the range of weights if the locus exhibits partial dominance and H is the dominant allele.

Communicating with tables. I am an Amazon researcher comparing different characteristics in species of frogs that live in very different environments. I use the Amazon green frog as my control since there is a lot of data on this particular frog and it lives on the rainforest floor. I then compare the other frogs to this control frog. I am looking at the length of the back leg, the distance between the eyes (the center of one eye to the center of the other eye), and the degree of webbing on the front foot.

I collected 50 frogs of each species (including the control Amazon green frog [AGF]) and then do unpaired t-test comparisons of each characteristic in the 4 test species to the same characteristic in the control species.

The p-values from my t-test comparisons are listed below which the species and characteristics that are being compared: AGF / brown swamp frog – length of back leg$$p=0.006$$AGF/yellow tree frog – the distance between eyes$$p=0.059$$AGF/red river frog – webbing$$p=0.035$$AGF/spotted stone frog – webbing$$p=0.004$$AGF/spotted stone frog – length of back leg$$p=0.0006$$AGF/brown swamp frog – the distance between eyes$$p=0.152$$AGF/ red river frog – the distance between eyes$$p=0.211$$AGF/yellow tree frog – length of back leg$$p=0.081$$AGF/spotted stone frog – the distance between eyes$$p=0.007$$AGF/yellow tree frog – webbing$$p=0.01E-15$$AGF/brown swamp frog – webbing$$p=0.003$$AGF/red river frog – length of back leg$$p=0.256$$As you can see I am not very organized, so you need to arrange these data into a clear, concise and understandable table (Table 1) that allows the reader to quickly comprehend what I have done.

Also, somehow denote, within the table, the statistically significant comparisons using$$0.05$$as the point of significance. Generally, the independent variable is used to label rows and the dependent labels columns. Once completed, copy/paste this table underneath Figure 5 on your other document. Once you are finished, convert your other document containing your five figures and one table to a .pdf and submit it on Canvas.