Cellular compartment
Some enzymes are only found in one cellular compartment, but other enzymes are found in more than one place. One example is malate dehydrogenase, which is found in both the cytoplasm and the mitochondrial matrix. 1) Explain the role of mitochondrial malate dehydrogenase. What reaction does this enzyme catalyze? 2) Explain the role of the cytoplasmic malate dehydrogenase. What reaction does this enzyme catalyze? 3) Why is it important for cells to have two versions of malate dehydrogenase?


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