How does chronic inflammation contribute to the pathogenesis of age-related diseases

How does chronic inflammation contribute to the pathogenesis of age-related diseases such as Alzheimer’s disease, osteoarthritis, and atherosclerosis, and what strategies can be employed to attenuate inflammatory processes and promote healthy aging? Chronic inflammation, characterized by sustained activation of immune responses and elevated levels of pro-inflammatory mediators, underlies the pathophysiology of various age-related conditions, contributing to tissue damage, dysfunction, and degeneration.