Decrease in ventricular contraction force

Heart failure, which involves a decrease in ventricular contraction force, is a common condition. Its is caused by an initiating event (such as a heart attach/myocardial infarction) which result in damage to the cardiomyocytes.

1)Why would damaged cardiomyocytes result in reduced ventricular contraction?

2)What is end diastolic and end systolic volume? Describe what may happen to end diastolic and systolic volumes with heart failure.

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