Glial Fibrillary Acidic Protein

Glial Fibrillary Acidic Protein (GFAP) plays an important role in brain development. Overexpression or downregulation of this protein could lead to neurodegenerative diseases such as Down syndrome (DS) and Alzheimer’s disease. In your experiment, you have a cell culture derived from DS mouse cerebral cortex tissue and sections of its whole brain. Suggest methods and describe the procedure that can be used to answer the objectives below: a) GFAP expression patterns in cell culture. b) GFAP expression patterns in different brain regions. Answer (min. 500 word):