Hypothyroidism and hyperthyroidism in terms of etiology, pathogenesis, clinical picture, diagnosis, and treatment rationale.

Hypothyroidism and hyperthyroidism in terms of etiology, pathogenesis, clinical picture, diagnosis, and treatment rationale.

This summary should cover hypothyroidism and hyperthyroidism, for each, you need to talk about:

1. Etiology:

• Most common causes of hypothyroidism in the U.S.
• Most common causes of hyperthyroidism in the U.S.

2. Pathogenesis:

Talk about the steps and the molecular mechanisms involved in the development of hypo-& hyperthyroidism and resulting in the clinical picture.

3. Clinical Picture:

• Signs& Symptoms: of Hypo- vs hyperthyroidism.
• Complications of hypothyroidism: Myxedema coma
• Complications of hyperthyroidism: Thyroid storm

4. Diagnosis:

• Measuring thyroid hormone levels and TSH and how to interpret results to differentiate between primary and secondary hypo- and hyperthyroidism.
• How to follow up the prognosis and response to treatment.

5. The pathophysiologic rationale of treatment:

Explain why we use certain medications for treating hypo-& hyperthyroidism in the light of understanding the pathophysiology involved.

This is the textbook for information:

McCance, K.L., Huether, S. E. (2018) Pathophysiology: The Biological Basis for Disease in Adults and Children. (8th Ed) St. Louis, MO. Elsevier Mosby ISBN-13: 978-0323583473 ISBN-10: 9780323583473