History of Intermittent pleuritic chest pain

Ms. X, a 32-year-old Hispanic woman, has had a history of intermittent pleuritic chest pain and joint pain for the past several years. Recently, she went to her physician because she noticed that an erythematous, butterfly-shaped rash had appeared on her face. Further lab tests indicated protein in her urine.

Her blood test indicated the presence of numerous antinuclear antibodies, especially anti-DNA, and mature neutrophils containing nuclear material. A diagnosis of systemic lupus erythematosus (SLE) was made. (Refer to Chapter 7, Immunity) Questions:

1. Lupus can mimic other conditions, and the condition manifests itself differently in each individual. What are some differential diagnoses that might be investigated and would need to be ruled out based on Ms.X’s symptoms before making the diagnosis of lupus?