Course of Intravenous antibiotics

A patient contracts C-difficile after a prolonged course of Intravenous antibiotics. This is an example of: MicroRNA failing to perform its function due to an overgrowth of C-difficile bacteria A situation that is unrelated to epigenetics The microbiome interacting with the epigenome to influence health status Methylation of intestinal cells by the antibiotic use which results in acute infection