The primary mechanism of action of organophosphate pesticides

The primary mechanism of action of organophosphate pesticides is the inhibition of carboxyl ester hydrolases, particularly acetylcholinesterase (AChE). AChE is an enzyme that degrades the neurotransmitter acetylcholine (ACh) into choline and acetic acid.

A. Explain why this can be lethal to insects.

B. How safe a pesticide would this be for humans? Explain