Which of the following is NOT a mechanism of catalysis used by enzymes?

Which of the following is NOT a mechanism of catalysis used by enzymes? Group of answer choices A) Forming a temporary covalent bond with substrate to facilitate the reaction. B) Binding more tightly to the transition state than the substrate. C) Correctly orienting substrates to interact. D) Forming a pH microenvironment to facilitate acid/base reactions E) Converting endergonic reactions to exergonic reactions