Pneumonia and pulmonary tuberculosis
Summarize the lung infections: pneumonia and pulmonary tuberculosis in terms of etiology, pathogenesis, clinical picture, diagnosis, and treatment rationale.
| The 5 General Topics of Disease Summary |
| 1. Etiology & risk factors |
| 2. Pathogenesis: The molecular mechanism of the disease process (How the disease process evolves) |
| 3. Clinical Picture: Signs& Symptoms, Sequelae, and Complications |
| 4. Diagnosis: Labs & tests (as well as screening tests and follow up tests whenever applicable) |
| 5. Pathophysiologic rationale of treatment |
Pneumonia
Etiology: Types of pneumonia (Community-acquired, Hospital-acquired, Ventilator-related). Major causative organisms in each type.
Pathogenesis: The 4 pathologic phases of lobar pneumonia (Congestion/Red Hepatization(aka: Consolidation)/ Grey Hepatization/ Resolution)
Clinical Picture: Signs and symptoms
Diagnosis: Chest X-ray findings. Indications of hospitalization
Pathologic rationale of treatment: e.g. when to suspect pseudomonas and which antibiotics are effective against it.
Pulmonary T.B.
Etiology: Causative bacteria, mode of transmission and risk factors
Pathogenesis: Steps from organism entry till symptom development
Clinical picture: Signs and symptoms
Diagnosis: Chest X-ray, sputum culture. Tuberculin skin test. Interferon Gamma Release Assay (IGRA) blood test.
Pathophysiologic Rationale of Treatment: For treating T.B. as well as asymptomatic Tuberculin-positive cases.
This is the textbook information McCance, K.L., Huether, S. E. (2018) Pathophysiology: The Biological Basis for Disease in Adults and Children. (8th Ed) St. Louis, MO. Elsevier Mosby ISBN-13: 978-0323583473 ISBN-10: 9780323583473
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