Predict the effect the mutation

Under each of the following conditions, please predict the effect the mutation will have on the rate at which glycolysis will proceed in liver cells: a. Loss of the allosteric site for ATP in phosphofructokinase b. Loss of binding site for citrate in phosphofructokinase c. Loss of the phosphatase domain of the bifunctional enzyme that controls the level of fructose 2,6-bisphosphate d. Loss of the binding site for fructose 1,6- bisphosphate in pyruvate kinase.