Regulation of blood pressure

Could you elaborate on the physiological mechanisms underlying the regulation of blood pressure and the role of the renin-angiotensin-aldosterone system (RAAS)? How does the juxtaglomerular apparatus in the kidneys detect changes in blood pressure and stimulate renin release, leading to the conversion of angiotensinogen to angiotensin I and its subsequent conversion to angiotensin II by angiotensin-converting enzyme (ACE)? Additionally, how does angiotensin II induce vasoconstriction, aldosterone release, and sodium retention, thereby increasing blood volume and elevating blood pressure? Furthermore, how do dysfunctions in the RAAS contribute to hypertension, cardiovascular disease, and renal disorders?

0 replies

Leave a Reply

Want to join the discussion?
Feel free to contribute!

Leave a Reply

Your email address will not be published. Required fields are marked *