Risk association between dietary fat intake

A case-control study design was utilized to investigate a possible risk association between dietary fat intake and pancreatic cancer. A group of 235 subjects with pancreatic cancer was identified from a regional tumor registry. Based on previous design considerations, a group of 515 age-matched subjects without pancreatic cancer were identified from a hospital discharge dataset in the same geographic region as the cases. All subjects consented to be interviewed regarding dietary fat consumption, and each was categorized based on current dietary fat intake recommendations as low, moderate, or high consumption. Results from the interview process are summarized below:

Group Pancreatic CA Cases Pancreatic CA Controls

Male / Low Consumption 40 50

Male / Moderate Consumption 55 140

Male / High Consumption 40 65

Female / Low Consumption 30 70

Female / Moderate Consumption 45 70

Female / High Consumption 25 20

A.        Estimate the risk association (Odds Ratio) between the moderate consumption group and the low consumption group for both sexes combined. Do the same calculation for males and females separately. Provide an interpretation of the results.

B.        Estimate the risk association (Odds Ratio) between the high consumption group and the low consumption group for both sexes combined. Do the same calculation for males and females separately. Provide an interpretation of the results.