Summarize the human immunodeficiency virus (HIV) in terms of etiology, pathogenesis, clinical picture, diagnosis, and treatment rationale.
Summarize the human immunodeficiency virus (HIV) in terms of etiology, pathogenesis, clinical picture, diagnosis, and treatment rationale.
The 5 General Topics of Disease Summary |
1. Etiology & risk factors |
2. Pathogenesis: The molecular mechanism of the disease process (How the disease process evolves) |
3. Clinical Picture: Signs& Symptoms, Sequelae, and Complications |
4. Diagnosis: Labs & tests (as well as screening tests and follow up tests whenever applicable) |
5. Pathophysiologic rationale of treatment |
- Etiology: Type of the causative virus and its characteristics. Mode of transmission.
- Pathogenesis: Which cell is infected by the virus (The CD-4 cell), and what are the steps the virus takes to infect this cell and reproduce inside (1. entry, 2. reverse-transcription, 3. Integration, 4. Assembly and release). The sequelae of infecting the CD-4 cells and how this affects the immune system.
- Clinical Picture: of HIV infection and the clinical picture of AIDS
- Diagnosis: Diagnostics to diagnose HIV, diagnose AIDS, and follow up the condition and prognosis.
- The pathophysiologic rationale of treatment: examples of drugs working at each of the 4 steps the virus takes to infect the CD-4 cell.
This is the textbook for information:
McCance, K.L., Huether, S. E. (2018) Pathophysiology: The Biological Basis for Disease in Adults and Children. (8th Ed) St. Louis, MO. Elsevier Mosby ISBN-13: 978-0323583473 ISBN-10: 9780323583473
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