The consequence of mutations
What would be the consequence of mutations in the TAP-1 or TAP-2 genes that resulted in non-functional proteins? a. there would be about half the MHC Class II molecules on the cell surface b. the immunoproteasome would not form properly C. intravesicular pathogens would not be killed by lysosomal enzymes d. there would be few if any MHC Class I molecules on the cell surface e. no peptides would be found in the MHC Class Il compartment


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