Discuss the ecological roles of microbial secondary metabolites in competition
Delve into the diverse metabolic pathways and secondary metabolite biosynthesis pathways employed by microorganisms to produce natural products with antimicrobial properties, including antibiotics, antifungals, and antiparasitics. Discuss the ecological roles of microbial secondary metabolites in competition, predation, and defense against pathogens, as well as their biotechnological applications in pharmaceutical discovery and drug development. Investigate novel approaches for antibiotic discovery, including genome mining, metagenomics, synthetic biology, and combinatorial biosynthesis, as well as strategies for overcoming antibiotic resistance and expanding the antibiotic repertoire against emerging infectious diseases.
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