Treatment of autoimmunity

For each of the therapeutic agents listed below, provide a brief explanation of the mechanism of action as a treatment of autoimmunity or recipients of organ transplantation.

1. Tacrolimus (FK506) & Cyclosporin A:
2. Corticosteroids (e.g. prednisone):
3. NASIDs (non-steroidal anti-inflammatory agents):
4. Humanized monoclonal antibody, anti-IL2R:
5. Cytotoxic agents (e.g. methotrexate, cyclophosphamide):