How do advances in genetics and genomics contribute to precision medicine approaches for cancer treatment

How do advances in genetics and genomics contribute to precision medicine approaches for cancer treatment, including targeted therapies and immunotherapy? Genetic and genomic profiling of tumors enables identification of driver mutations, biomarkers, and molecular subtypes that inform personalized treatment strategies tailored to individual patients’ genetic makeup and tumor characteristics. Targeted therapies, such as tyrosine kinase inhibitors and monoclonal antibodies, selectively inhibit aberrant signaling pathways or immune checkpoints implicated in cancer progression, while immunotherapy harnesses the body’s immune system to recognize and eradicate tumor cells. Integrating these precision medicine approaches into clinical practice improves treatment efficacy, reduces adverse effects, and prolongs survival for cancer patients across diverse tumor types.

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