Human immunodeficiency virus (HIV)
Summarize the human immunodeficiency virus (HIV) in terms of etiology, pathogenesis, clinical picture, diagnosis, and treatment rationale.
| The 5 General Topics of Disease Summary |
| 1. Etiology & risk factors |
| 2. Pathogenesis: The molecular mechanism of the disease process (How the disease process evolves) |
| 3. Clinical Picture: Signs& Symptoms, Sequelae, and Complications |
| 4. Diagnosis: Labs & tests (as well as screening tests and follow up tests whenever applicable) |
| 5. Pathophysiologic rationale of treatment |
- Etiology: Type of the causative virus and its characteristics. Mode of transmission.
- Pathogenesis: Which cell is infected by the virus (The CD-4 cell), and what are the steps the virus takes to infect this cell and reproduce inside (1. entry, 2. reverse-transcription, 3. Integration, 4. Assembly and release). The sequelae of infecting the CD-4 cells and how this affects the immune system.
- Clinical Picture: of HIV infection and the clinical picture of AIDS
- Diagnosis: Diagnostics to diagnose HIV, diagnose AIDS, and follow up the condition and prognosis.
- The pathophysiologic rationale of treatment: examples of drugs working at each of the 4 steps the virus takes to infect the CD-4 cell.
This is the textbook for information:
McCance, K.L., Huether, S. E. (2018) Pathophysiology: The Biological Basis for Disease in Adults and Children. (8th Ed) St. Louis, MO. Elsevier Mosby ISBN-13: 978-0323583473 ISBN-10: 9780323583473
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