Pathophysiological Connections

Using migraine headache as an example:

1. Pathophysiological Connections: Explain the pathophysiology and draw connections to the specific findings of the primary diagnosis, including a comparison of these findings with normal physiology.
2. Pharmacotherapeutics: Describe potential pharmacotherapeutic options, including a first-line drug therapy option and at least one second-line or third-line option, for this case based on current clinical practice guidelines. Include considerations for complementary medicine in your response.
3. Age-Related Changes: Examine how age-related changes in the body system would affect your pharmacotherapeutic decisions.